产品货号：
Z28178
中文名称：
TGFBR2抗体
英文名称：
Anti-TGFBR2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TGFBR2 Antibody |
| 指标别名 | AAT3;FAA3;LDS1B;LDS2B;MFS2;RIIC;TAAD2;TbetaR II;TGF beta receptor type 2;TGF beta receptor type II;TGF beta type II receptor;TGFbeta RII;TGFBR2;TGFR 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | TGFBR2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human TGF beta Receptor II(330-346aa KGNLQEYLTRHVISWED),identical to the related rat and mouse sequences. |
| 实际分子量 | 65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TGFBR2(transforming growth factor,beta receptor II(70/80kDa)),also known as TGF-beta receptor type-2,TGFR-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II(TGF-beta receptor type II,TbetaR-II),is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily.A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of approximately 60kD in length.The encoded protein is a transmembrane protein that has a protein kinase domain,forms a heterodimeric complex with another receptor protein,and binds TGF-beta.This receptor/ligand complex phosphorylates proteins,which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.Mutations in this gene have been associated with?Marfan syndrome,?Loeys-Deitz aortic aneurysm syndrome,?Osler-Weber-Rendu syndrome,and the development of various types of tumors.Alternatively spliced transcript variants encoding different isoforms have been characterized.TGFBR2 may be a target of the EWS-FLI1 fusion protein found in Ewing sarcoma and related peripheral primitive neuroectodermal tumors. |
| Uniprot ID | P37173 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | transforming growth factor,beta receptor II(70/80kDa) |
| 蛋白名全称 | TGF-beta receptor type-2(TGFR-2) |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：TGFBR2抗体，TGFBR2多抗，Anti-TGFBR2 Antibody